Critical appraisal:Hage M, Siersema PD, van Dekken H, Steyerberg EW, Dees J, Kuipers EJ 2004

From Cancer Guidelines Wiki

Critical Appraisal

Article being appraised

Hage M, Siersema PD, van Dekken H, Steyerberg EW, Dees J, Kuipers EJ. Oesophageal cancer incidence and mortality in patients with long-segment Barrett's oesophagus after a mean follow-up of 12.7 years. Scand J Gastroenterol 2004 Dec;39(12):1175-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/15742992.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

105



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Selected group (debateable whether group is representative e.g. consecutive sample but extensive exclusion criteria)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

A total of 105 patients were included in the study. The mean FUP period was 12.7 years (range 0.3-25.5 years), accounting for a total of 1329 patient-years of fUP. At the end of FUP, 6/105 patients developed adenocarcinoma, equals to one cancer case per 221 patient-years.

Completed by

Ms Qingwei Luo


Jutta's tick icon.png This appraisal has been completed.


Article
Hage M, Siersema PD, van Dekken H, Steyerberg EW, Dees J, Kuipers EJ. Oesophageal cancer incidence and mortality in patients with long-segment Barrett's oesophagus after a mean follow-up of 12.7 years. Scand J Gastroenterol 2004 Dec;39(12):1175-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/15742992.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment