Critical appraisal:Hage M, Siersema PD, van Dekken H, Steyerberg EW, Dees J, Kuipers EJ 2004
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Critical Appraisal
Article being appraised
Hage M, Siersema PD, van Dekken H, Steyerberg EW, Dees J, Kuipers EJ. Oesophageal cancer incidence and mortality in patients with long-segment Barrett's oesophagus after a mean follow-up of 12.7 years. Scand J Gastroenterol 2004 Dec;39(12):1175-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/15742992.
Applicable clinical question
Key Facts
Study Design
prevalence and incidence study
Number of Patients:
105
Evidence ratings
Risk of bias
| High risk of bias | Comments: Please replace this text and include any additional comments in regards to your quality rating |
Result of appraisal
Included
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- Article
- Hage M, Siersema PD, van Dekken H, Steyerberg EW, Dees J, Kuipers EJ. Oesophageal cancer incidence and mortality in patients with long-segment Barrett's oesophagus after a mean follow-up of 12.7 years. Scand J Gastroenterol 2004 Dec;39(12):1175-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/15742992.
- Assigned to
- User:Freddy.sitas
- Topic area
- Guidelines:Barrett's
- Clinical question
Section below only relevant for Cancer Council Project Officer
A total of 105 patients were included in the study. The mean FUP period was 12.7 years (range 0.3-25.5 years), accounting for a total of 1329 patient-years of fUP. At the end of FUP, 6/105 patients developed adenocarcinoma, equals to one cancer case per 221 patient-years.