Critical appraisal:Horwhat JD, Baroni D, Maydonovitch C, Osgard E, Ormseth E, Rueda-Pedraza E, et al 2007

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Critical Appraisal

Article being appraised

Horwhat JD, Baroni D, Maydonovitch C, Osgard E, Ormseth E, Rueda-Pedraza E, et al. Normalization of intestinal metaplasia in the esophagus and esophagogastric junction: incidence and clinical data. Am J Gastroenterol 2007 Mar;102(3):497-506 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17156135.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

148



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Selected group (debateable whether group is representative e.g. consecutive sample but extensive exclusion criteria)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
No or not described
Result of appraisal

Jutta's tick icon.png Included



Comments

Patients from single medical centre, complete FUP data on 68% of the entire cohort was gathered (n=101). The incidence of developing dysplasia or cancer was 7/23 in long-segment BO, 3/44 in short-segment BO, and 0/34 in esophagogastric junction specialized intestinal metaplasia patients.

Completed by

Ms Qingwei Luo


Jutta's tick icon.png This appraisal has been completed.


Article
Horwhat JD, Baroni D, Maydonovitch C, Osgard E, Ormseth E, Rueda-Pedraza E, et al. Normalization of intestinal metaplasia in the esophagus and esophagogastric junction: incidence and clinical data. Am J Gastroenterol 2007 Mar;102(3):497-506 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17156135.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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