Critical appraisal:Hughes MJ, Chowdhry MF, Woolley SM, Walker WS 2011

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Critical Appraisal

Article being appraised

Hughes MJ, Chowdhry MF, Woolley SM, Walker WS. In patients undergoing lung resection for non-small cell lung cancer, is lymph node dissection or sampling superior? Interact Cardiovasc Thorac Surg 2011 Sep;13(3):311-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21606053.


Applicable clinical question

Key Facts

Study Design

systematic review — Both Randomised and Non-randomised, but randomised then considered in isolation for results and conclusion.

Number of Patients:

1401


Includes an economic evaluation

no

Evidence ratings

Level of evidence

I

Risk of bias
Low risk of bias Comments: Clearly focused question. Appropriate search strategy. Results summarised with quality assessment. Large numbers of patients. 4 RCTs. Good follow-up overall.


Size of effect
1 Reason for decision: A clinically important benefit for the full range of plausible estimates. The confidence limit closest to the measure of no effect (the ‘null’) rules out a clinically unimportant effect of the intervention.
Relevance of evidence
1 Additional comments: Evidence of an effect on patient‐relevant clinical outcomes including benefits and harms, quality of life and survival.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Associate Professor Gavin Wright MD FRACS PhD


Jutta's tick icon.png This appraisal has been completed.


Article
Hughes MJ, Chowdhry MF, Woolley SM, Walker WS. In patients undergoing lung resection for non-small cell lung cancer, is lymph node dissection or sampling superior? Interact Cardiovasc Thorac Surg 2011 Sep;13(3):311-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21606053.
Assigned to
User:Gavin.wright
Topic area
Guidelines:Lung cancer/Treatment/Non-small-cell stage III operable
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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