Critical appraisal:Ichinose M, Fujimoto A, Osuga Y, Minaguchi T, Kawana K, Yano T, et al 2013 3

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Critical Appraisal

Article being appraised

Ichinose M, Fujimoto A, Osuga Y, Minaguchi T, Kawana K, Yano T, et al. The influence of infertility treatment on the prognosis of endometrial cancer and atypical complex endometrial hyperplasia. Int J Gynecol Cancer 2013 Feb;23(2):288-93 Available from: http://www.ncbi.nlm.nih.gov/pubmed/23314282.


Applicable clinical question

Key Facts

Study Design

cohort study, risk factors

Number of Patients:

36

Results of outcome(s):

The clinical outcomes of 36 patients were investigated. Twenty-six of them desired to conceive soon after complete response. All of them underwent infertility treatment, and 16 women delivered healthy babies. Kaplan-Meyer curve and log-rank test analysis revealed that women who achieved live birth had a significantly lower risk of recurrence than those without live birth. There was not a significant difference between the patients with and without infertility treatment.

Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-2

Risk of bias
High risk of bias Comments:
Result of appraisal

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Article
Ichinose M, Fujimoto A, Osuga Y, Minaguchi T, Kawana K, Yano T, et al. The influence of infertility treatment on the prognosis of endometrial cancer and atypical complex endometrial hyperplasia. Int J Gynecol Cancer 2013 Feb;23(2):288-93 Available from: http://www.ncbi.nlm.nih.gov/pubmed/23314282.
Assigned to
User:Jessica.harris
Topic area
Guidelines:COSA:Cancer fertility preservation guidelines/Assisted reproduction for cancer survivors
Clinical question
Form
Form:Critical appraisal


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