Critical appraisal:Jung KW, Talley NJ, Romero Y, Katzka DA, Schleck CD, Zinsmeister AR, et al 2011 2

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Critical Appraisal

Article being appraised

Jung KW, Talley NJ, Romero Y, Katzka DA, Schleck CD, Zinsmeister AR, et al. Epidemiology and natural history of intestinal metaplasia of the gastroesophageal junction and Barrett's esophagus: a population-based study. Am J Gastroenterol 2011 Aug;106(8):1447-55; quiz 1456 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21483461.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

401



Evidence ratings

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Selected group (multiple institutions)
Subject (sample) selection
Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Reasonable follow-up (>80%)
Result of appraisal

Jutta's tick icon.png Included



Comments

Median follow up period of 7.8 years.
Rate of 2.9 oesophageal adenocarcinomas per 1000 person-years.
Rate of 5.0 high grade dysplasias per 1000 person-years.

The percentage follow up is not stated, but is assumed to be at least "reasonable" as over 80% of the county population attends one of the county's two health centres annually.

Completed by

Peter Sarich


Jutta's tick icon.png This appraisal has been completed.


Article
Jung KW, Talley NJ, Romero Y, Katzka DA, Schleck CD, Zinsmeister AR, et al. Epidemiology and natural history of intestinal metaplasia of the gastroesophageal junction and Barrett's esophagus: a population-based study. Am J Gastroenterol 2011 Aug;106(8):1447-55; quiz 1456 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21483461.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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