Critical appraisal:Kelty CJ, Gough MD, Van Wyk Q, Stephenson TJ, Ackroyd R 2007

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Critical Appraisal

Article being appraised

Kelty CJ, Gough MD, Van Wyk Q, Stephenson TJ, Ackroyd R. Barrett's oesophagus: intestinal metaplasia is not essential for cancer risk. Scand J Gastroenterol 2007 Nov;42(11):1271-4 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17852872.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

688


Includes an economic evaluation

no

Evidence ratings

Risk of bias
High risk of bias Comments: Single-centre teaching hospital cohort.

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Highly selected (selection at clinician's discretion regardless of whether sample consecutive), unclear or not described
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

Of 688 patients, 28 developed adenocarcinoma (4.1%, 0.34% a year), median follow-up of 12 years (range 8-20 years).

Completed by

Ms Qingwei Luo


Jutta's tick icon.png This appraisal has been completed.


Article
Kelty CJ, Gough MD, Van Wyk Q, Stephenson TJ, Ackroyd R. Barrett's oesophagus: intestinal metaplasia is not essential for cancer risk. Scand J Gastroenterol 2007 Nov;42(11):1271-4 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17852872.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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