Critical appraisal:Kwekkeboom KL, Wanta B, Bumpus M 2008

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Critical Appraisal

Article being appraised

Kwekkeboom KL, Wanta B, Bumpus M. Individual difference variables and the effects of progressive muscle relaxation and analgesic imagery interventions on cancer pain. J Pain Symptom Manage 2008 Dec;36(6):604-15 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18504089.


Applicable clinical question

Key Facts

Study Design

randomised controlled trial

Number of Patients:

40


Includes an economic evaluation

no

Evidence ratings

Level of evidence

II

Risk of bias
Moderate risk of bias Comments: This is a well designed study with understandably small numbers. It may be underpowered to infer differences in CBT strategies for individuals with specific psychological features


Size of effect
2 Reason for decision: It is very difficult to give one estimate for this given the non-uniform response. A further qualifier is that a large number of patients elected not to participate and it is possible that pre-selection occurred that would have an effect on the generalisability of the results
Relevance of evidence
1 Additional comments: Essentially covered above.There are demonstrable effects but they are inconsistent and short-term. That said, for a patient who is suitable, the preferred technique could be useful as an ancillary treatment for short-term increments in cancer pain
Result of appraisal

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Completed by

Prof Matthew Peters MD FRACP


Jutta's tick icon.png This appraisal has been completed.


Article
Kwekkeboom KL, Wanta B, Bumpus M. Individual difference variables and the effects of progressive muscle relaxation and analgesic imagery interventions on cancer pain. J Pain Symptom Manage 2008 Dec;36(6):604-15 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18504089.
Assigned to
User:Matthew.peters
Topic area
Guidelines:Lung cancer/Treatment/Non-small-cell stage IV inoperable
Clinical question
Form
Form:Critical appraisal


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