Critical appraisal:Ladanyi C, Mor A, Christianson MS, Dhillon N, Segars JH 2017

Critical Appraisal

Article being appraised

Ladanyi C, Mor A, Christianson MS, Dhillon N, Segars JH. Recent advances in the field of ovarian tissue cryopreservation and opportunities for research. J Assist Reprod Genet 2017 Jun;34(6):709-722 Available from: http://www.ncbi.nlm.nih.gov/pubmed/28365839.

Applicable clinical question

• In female cancer patients does ovarian tissue cryopreservation result in pregnancy and livebirth? Is there any reduction in the quality of oocytes/follicles? Can transplantation restore pubertal development? Are there any risks involved?

Key Facts

Study Design

systematic review

Number of Patients:

80

Evidence ratings

Level of evidence

IV

Risk of bias

Low risk of bias

Comments:

Size of effect

5	Reason for decision:

Relevance of evidence

1	Additional comments:

Result of appraisal

Included

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This appraisal has been completed.

Article

Ladanyi C, Mor A, Christianson MS, Dhillon N, Segars JH. Recent advances in the field of ovarian tissue cryopreservation and opportunities for research. J Assist Reprod Genet 2017 Jun;34(6):709-722 Available from: http://www.ncbi.nlm.nih.gov/pubmed/28365839.

Assigned to

User:Kate.stern

Topic area

Guidelines:COSA:Cancer fertility preservation guidelines/Options for treatment

Clinical question

• In female cancer patients does ovarian tissue cryopreservation result in pregnancy and livebirth? Is there any reduction in the quality of oocytes/follicles? Can transplantation restore pubertal development? Are there any risks involved?

Form

Form:Critical appraisal

Section below only relevant for Cancer Council Project Officer

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