Critical appraisal:Lim CH, Treanor D, Dixon MF, Axon AT 2007

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Critical Appraisal

Article being appraised

Lim CH, Treanor D, Dixon MF, Axon AT. Low-grade dysplasia in Barrett's esophagus has a high risk of progression. Endoscopy 2007 Jul;39(7):581-7 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17611911.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

357


Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-2

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Highly selected (selection at clinician's discretion regardless of whether sample consecutive), unclear or not described
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

There were 357 patients with BO. After 8 years, HGD or esophageal cancer had developed in 25/356 patients with BO. The overall incidence of cancer was 1 per 160 patient−years’ follow−up.

Completed by

Ms Qingwei Luo


Jutta's tick icon.png This appraisal has been completed.


Article
Lim CH, Treanor D, Dixon MF, Axon AT. Low-grade dysplasia in Barrett's esophagus has a high risk of progression. Endoscopy 2007 Jul;39(7):581-7 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17611911.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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