Critical appraisal:May A, Gossner L, Behrens A, Kohnen R, Vieth M, Stolte M, et al 2003

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Critical Appraisal

Article being appraised

May A, Gossner L, Behrens A, Kohnen R, Vieth M, Stolte M, et al. A prospective randomized trial of two different endoscopic resection techniques for early stage cancer of the esophagus. Gastrointest Endosc 2003 Aug;58(2):167-75 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/12872081.


Applicable clinical question

Key Facts

Study Design

randomised controlled trial

Number of Patients:

72


Includes an economic evaluation

no

Evidence ratings

Level of evidence

II

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: randomised controlled trial

Was the trial double-blinded?
Outcomes not blinded, substantial side-effects, or not reported.
Was the treatment allocation schedule concealed?
Adequately concealed (e.g. central randomisation, numbered or coded bottles, drugs prepared by pharmacy).
Were all randomised participants included in the analysis?
Exclusions not likely to cause bias (>80% follow-up for all groups, <5% difference in follow-up between groups)
The field below is not considered when calculating the risk of bias rating
How was the allocation schedule generated?
Adequate (e.g. random number table, computer random generator, coin tossing, card shuffling)
Size of effect
4 Reason for decision: The two techniques had no significant difference in terms of resection specimen or complications.
Relevance of evidence
1 Additional comments: 2 techniques of EMR are equivalent in terms of efficacy and safety.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Farzan Fahrtash Bahin, MBBS (Hons), MPhil (Med)


Jutta's tick icon.png This appraisal has been completed.


Article
May A, Gossner L, Behrens A, Kohnen R, Vieth M, Stolte M, et al. A prospective randomized trial of two different endoscopic resection techniques for early stage cancer of the esophagus. Gastrointest Endosc 2003 Aug;58(2):167-75 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/12872081.
Assigned to
User:Michael.bourke
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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