Critical appraisal:Miros M, Kerlin P, Walker N 1991 3

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Critical Appraisal

Article being appraised

Miros M, Kerlin P, Walker N. Only patients with dysplasia progress to adenocarcinoma in Barrett's oesophagus. Gut 1991 Dec;32(12):1441-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/1773946.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

124



Evidence ratings

Risk of bias
High risk of bias Comments: Single institution study to determine the incidence of cancer in patients with and without histological evidence of dysplasia. Of 124 eligible patients, 43 lost to follow-up (12 dead, 31 refused follow up).

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

Incidence of cancer 1037/100000 pyar

Completed by

David Whiteman


Jutta's tick icon.png This appraisal has been completed.


Article
Miros M, Kerlin P, Walker N. Only patients with dysplasia progress to adenocarcinoma in Barrett's oesophagus. Gut 1991 Dec;32(12):1441-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/1773946.
Assigned to
User:Henry.to
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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