Critical appraisal:Mukai M, Oida Y, Tajima T, Kishima K, Ninomiya H, Sato S, et al 2006 2

Risk of bias assessment: cohort study

Subject selection

"New technology" group

Selected group

Comparison group

Selected group

Comparability of groups on demographic characteristics and clinical features

Not comparable and not adjusted for differences

Measurement of outcomes

Outcome measures blind to technology used

No, but objective measures used

Same method of measurement used across comparison groups

Yes

Completeness of follow-up

Was follow-up complete and were all patients included in the analysis?

No or not described

Overall risk of bias

High risk of bias

Additional comments: Please replace this text and include any additional comments in regards to your risk of bias rating

Comments

"New technology" group - 1) an age of <75 years, 2) a performance status of 0 or 1 (Japan Clinical Oncology Group; JCOG), and 3) complete medical records and follow-up data on recurrence and survival.

 Highly selected or not described

This appraisal has been completed.

Article

Mukai M, Oida Y, Tajima T, Kishima K, Ninomiya H, Sato S, et al. Alternating hepatic arterial infusion and systemic chemotherapy for stage IV colorectal cancer with synchronous liver metastasis. Oncol Rep 2006 Oct;16(4):865-70 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16969507.

Assigned to

User:Verity.chadwick

Topic area

Guidelines:Colorectal cancer

Clinical question

• MNG14: Which patients with resectable synchronous or metachronous metastatic colon or rectal cancer are suitable for curative surgery?

Form

Form:Quality appraisal cohort

Section below only relevant for Cancer Council Project Officer

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