Critical appraisal:Mukai M, Oida Y, Tajima T, Kishima K, Ninomiya H, Sato S, et al 2006 2

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Risk of bias assessment: cohort study

Subject selection
"New technology" group
Selected group
Comparison group
Selected group
Comparability of groups on demographic characteristics and clinical features
Not comparable and not adjusted for differences
Measurement of outcomes
Outcome measures blind to technology used
No, but objective measures used
Same method of measurement used across comparison groups
Yes
Completeness of follow-up
Was follow-up complete and were all patients included in the analysis?
No or not described
Overall risk of bias
High risk of bias Additional comments: Please replace this text and include any additional comments in regards to your risk of bias rating
Comments

"New technology" group - 1) an age of <75 years, 2) a performance status of 0 or 1 (Japan Clinical Oncology Group; JCOG), and 3) complete medical records and follow-up data on recurrence and survival.

 Highly selected or not described


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Article
Mukai M, Oida Y, Tajima T, Kishima K, Ninomiya H, Sato S, et al. Alternating hepatic arterial infusion and systemic chemotherapy for stage IV colorectal cancer with synchronous liver metastasis. Oncol Rep 2006 Oct;16(4):865-70 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16969507.
Assigned to
User:Verity.chadwick
Topic area
Guidelines:Colorectal cancer
Clinical question
Form
Form:Quality appraisal cohort


Section below only relevant for Cancer Council Project Officer

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