Critical appraisal:Murali R, Shaw HM, Lai K, McCarthy SW, Quinn MJ, Stretch JR, et al 2010
Critical Appraisal
Murali R, Shaw HM, Lai K, McCarthy SW, Quinn MJ, Stretch JR, et al. Prognostic factors in cutaneous desmoplastic melanoma: a study of 252 patients. Cancer 2010 Sep 1;116(17):4130-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/20564101.
Key Facts
case series
To determine the value of sentinel lymph node biopsy in patients with primary cutaneous melanoma tumors that exhibited desmoplasia and analysed the prognostic value of various clinicopatholic factors in these patients. To determine whether extent of desmoplasia was predictive of sentinel lymph node tumour-harbouring status and clinical outcome.
252
rate of sentinel node metastasis
17/252 patients were had sentinel node metastasis (6.7%).
no
Evidence ratings
IV
High risk of bias | Comments: Please replace this text and include any additional comments in regards to your risk of bias rating |
5 | Reason for decision: Please replace this text and briefly describe the reasons for your rating |
2 | Additional comments: Please replace this text and briefly describe the reasons for your rating |
- Article
- Murali R, Shaw HM, Lai K, McCarthy SW, Quinn MJ, Stretch JR, et al. Prognostic factors in cutaneous desmoplastic melanoma: a study of 252 patients. Cancer 2010 Sep 1;116(17):4130-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/20564101.
- Assigned to
- User:Cecilia.taing
- Topic area
- Guidelines:Melanoma
- Clinical question
Section below only relevant for Cancer Council Project Officer