Critical appraisal:Murray L, Watson P, Johnston B, Sloan J, Mainie IM, Gavin A 2003

Critical Appraisal

Article being appraised

Murray L, Watson P, Johnston B, Sloan J, Mainie IM, Gavin A. Risk of adenocarcinoma in Barrett's oesophagus: population based study. BMJ 2003 Sep 6;327(7414):534-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/12958113.

Applicable clinical question

• What is the incidence of neoplasia in patients with BO?

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

2969

Includes an economic evaluation

no

Evidence ratings

Level of evidence

II

Risk of bias

Low risk of bias

Comments: Please replace this text and include any additional comments in regards to your quality rating

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Risk of bias assessment: prevalence and incidence study

Source population of patients

Population based

Subject (sample) selection

Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)

Measurement of condition

Objective and reliable (based on registry or other equivalent source)

Follow-up complete and all patients included in the analysis?

Yes (follow-up >95%)

Result of appraisal

Included

Comments

Population-based cohort study, There were 2969 patients with BO. The mean FUP was 3.7 (range 1 to 8) years, with 29 oesophageal malignancies found.

Completed by

Ms Qingwei Luo

This appraisal has been completed.

Article

Murray L, Watson P, Johnston B, Sloan J, Mainie IM, Gavin A. Risk of adenocarcinoma in Barrett's oesophagus: population based study. BMJ 2003 Sep 6;327(7414):534-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/12958113.

Assigned to

User:Freddy.sitas

Topic area

Guidelines:Barrett's

Clinical question

• What is the incidence of neoplasia in patients with BO?

Form

Form:Critical appraisal

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