Critical appraisal:Navaneethan U, Kochhar G, Venkatesh PG, Lewis B, Lashner BA, Remzi FH, et al 2012 1

Risk of bias assessment: cohort study

Subject selection

"New technology" group

Selected group

Comparison group

Selected group

Comparability of groups on demographic characteristics and clinical features

Not comparable but adjusted analysis used

Measurement of outcomes

Outcome measures blind to technology used

No, but objective measures used

Same method of measurement used across comparison groups

Yes

Completeness of follow-up

Was follow-up complete and were all patients included in the analysis?

Yes (follow-up >95%) or survival analysis using all patients

Overall risk of bias

Moderate risk of bias

Additional comments: Please replace this text and include any additional comments in regards to your risk of bias rating

This appraisal has been completed.

Article

Navaneethan U, Kochhar G, Venkatesh PG, Lewis B, Lashner BA, Remzi FH, et al. Duration and severity of primary sclerosing cholangitis is not associated with risk of neoplastic changes in the colon in patients with ulcerative colitis. Gastrointest Endosc 2012 May;75(5):1045-1054.e1 Available from: http://www.ncbi.nlm.nih.gov/pubmed/22405258.

Assigned to

User:Cecilia.taing

Topic area

Guidelines:Colorectal cancer/Colonoscopy surveillance

Clinical question

• What is the appropriate time to commence surveillance in IBD patients (ulcerative colitis and Crohn’s patients, and effects of primary sclerosing cholangitis or family history of CRC)?

Form

Form:Quality appraisal cohort

Outcomes

Colorectal Cancer risk

Section below only relevant for Cancer Council Project Officer

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