Critical appraisal:Neuhaus H, Terheggen G, Rutz EM, Vieth M, Schumacher B 2012
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Critical Appraisal
Article being appraised
Neuhaus H, Terheggen G, Rutz EM, Vieth M, Schumacher B. Endoscopic submucosal dissection plus radiofrequency ablation of neoplastic Barrett's esophagus. Endoscopy 2012 Dec;44(12):1105-13 Available from: http://www.ncbi.nlm.nih.gov/pubmed/22968641.
Applicable clinical question
Key Facts
Study Design
case series
Number of Patients:
30
Includes an economic evaluation
no
Evidence ratings
Level of evidence
IV
Risk of bias
High risk of bias | Comments: single centre series, median follow up 17 months
ESD for HGD/EOA followed by RFA for remaining Barrett's mucosa |
Size of effect
2 | Reason for decision: En-bloc resection rate 90% , R0 resection rate 39% complete remission of neoplasia 97% at median 17 months |
Relevance of evidence
2 | Additional comments: Please replace this text and briefly describe the reasons for your rating |
Result of appraisal
Completed by
- Article
- Neuhaus H, Terheggen G, Rutz EM, Vieth M, Schumacher B. Endoscopic submucosal dissection plus radiofrequency ablation of neoplastic Barrett's esophagus. Endoscopy 2012 Dec;44(12):1105-13 Available from: http://www.ncbi.nlm.nih.gov/pubmed/22968641.
- Assigned to
- User:Michael.bourke
- Topic area
- Guidelines:Barrett's
- Clinical question
Section below only relevant for Cancer Council Project Officer