Critical appraisal:Northouse LL, Mood DW, Schafenacker A, Kalemkerian G, Zalupski M, LoRusso P, et al 2013

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Critical Appraisal

Article being appraised

Northouse LL, Mood DW, Schafenacker A, Kalemkerian G, Zalupski M, LoRusso P, et al. Randomized clinical trial of a brief and extensive dyadic intervention for advanced cancer patients and their family caregivers. Psychooncology 2013 Mar;22(3):555-63 Available from: http://www.ncbi.nlm.nih.gov/pubmed/22290823.


Applicable clinical question

Key Facts

Study Design

randomised controlled trial

Study aims:

The study examined whether patient-carer giver dyads allocated to a brief or extensive dyadic intervention had better outcomes than dyads allocated to care as usual. The intervention offered dyads support and information. The brief intervention included two 90 minutes home visits and one 30-minutes phone call. The extensive intervention included four 90 minute home visits and 2 30-minutes phone calls. Both programs were of 10 week duration.

Number of Patients:

484

484 dyads were stratified of which 141 had lung cancer. The final sample was 302 dyads
Reported outcome(s):

Outcome measures included: distress, appraisal of illness, appraisal of care-giving, uncertainty, hopelessness. coping strategies, self-efficacy, quality of life and dyadic support

Results of outcome(s):

The study found that both the brief and extensive dyad programs led to improvement in dyad coping, self-efficacy, quality of life. Most effects were found at 3 months.

Includes an economic evaluation

no

Evidence ratings

Level of evidence

II

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: randomised controlled trial

Was the trial double-blinded?
No response
Was the treatment allocation schedule concealed?
No response
Were all randomised participants included in the analysis?
No response
The field below is not considered when calculating the risk of bias rating
How was the allocation schedule generated?
Adequate (e.g. random number table, computer random generator, coin tossing, card shuffling)
Size of effect
1 Reason for decision: The study couldn't determine intervention dose but they found that both interventions led to significant improvements in dyad coping, self-efficacy, quality of life. The study had a modest sample size
Relevance of evidence
1 Additional comments: The study examined impact of intervention on patient relevant outcomes including distress, self-efficacy and quality of life.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Maria Ftanou BAppSc(Hons) Dpsych Clinical


Jutta's tick icon.png This appraisal has been completed.


Article
Northouse LL, Mood DW, Schafenacker A, Kalemkerian G, Zalupski M, LoRusso P, et al. Randomized clinical trial of a brief and extensive dyadic intervention for advanced cancer patients and their family caregivers. Psychooncology 2013 Mar;22(3):555-63 Available from: http://www.ncbi.nlm.nih.gov/pubmed/22290823.
Assigned to
User:Maria.ftanou
Topic area
Guidelines:Lung cancer
Clinical question
Form
Form:Critical appraisal
Study design
randomised controlled trial
Level of Evidence
II

Section below only relevant for Cancer Council Project Officer

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