Critical appraisal:Orman ES, Kim HP, Bulsiewicz WJ, Cotton CC, Dellon ES, Spacek MB, et al 2012 2

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Critical Appraisal

Article being appraised

Orman ES, Kim HP, Bulsiewicz WJ, Cotton CC, Dellon ES, Spacek MB, et al. Intestinal Metaplasia Recurs Infrequently in Patients Successfully Treated for Barrett's Esophagus With Radiofrequency Ablation. Am J Gastroenterol 2012 Dec 18 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23247578.


Applicable clinical question

Key Facts

Study Design

cohort study

Number of Patients:

89


Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-3

Risk of bias
Moderate risk of bias Comments: single centre; overall recurrence rate post eradication of BE is 5.2% per year

Risk of bias assessment: cohort study

Subject selection
"New technology" group
Selected group
Comparison group
Selected group
Comparability of groups on demographic characteristics and clinical features
Not comparable but adjusted analysis used
Measurement of outcomes
Outcome measures blind to technology used
No, but objective measures used
Same method of measurement used across comparison groups
Yes
Completeness of follow-up
Was follow-up complete and were all patients included in the analysis?
Reasonable follow-up of all groups (>80%)
Size of effect
3 Reason for decision: No predictive factors for recurrence or progression
Relevance of evidence
4 Additional comments: low number of EOA cases (17), median follow up 13 months
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Farzan Fahrtash Bahin, MBBS (Hons), MPhil (Med)


Jutta's tick icon.png This appraisal has been completed.


Article
Orman ES, Kim HP, Bulsiewicz WJ, Cotton CC, Dellon ES, Spacek MB, et al. Intestinal Metaplasia Recurs Infrequently in Patients Successfully Treated for Barrett's Esophagus With Radiofrequency Ablation. Am J Gastroenterol 2012 Dec 18 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23247578.
Assigned to
User:Michael.bourke
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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