Critical appraisal:Palmer JD, Schneider CJ, Hockstein N, Hanlon AL, Silberg J, Strasser J, et al 2018

Risk of bias assessment: cohort study

Subject selection

"New technology" group

Selected group

Comparison group

Selected group

Comparability of groups on demographic characteristics and clinical features

Comparable

Measurement of outcomes

Outcome measures blind to technology used

No, but objective measures used

Same method of measurement used across comparison groups

Yes

Completeness of follow-up

Was follow-up complete and were all patients included in the analysis?

Yes (follow-up >95%) or survival analysis using all patients

Overall risk of bias

Moderate risk of bias

Additional comments:

This appraisal has been completed.

Article

Palmer JD, Schneider CJ, Hockstein N, Hanlon AL, Silberg J, Strasser J, et al. Combination of post-operative radiotherapy and cetuximab for high-risk cutaneous squamous cell cancer of the head and neck: A propensity score analysis. Oral Oncol 2018 Mar;78:102-107 Available from: http://www.ncbi.nlm.nih.gov/pubmed/29496036.

Assigned to

User:Albert.chetcuti

Topic area

Guidelines:Keratinocyte carcinoma

Clinical question

• What should be the protocol to manage or treat locoregionally advanced cutaneous squamous cell carcinoma?

Form

Form:Quality appraisal cohort

Outcomes

Overall survival; Progression-free survival

Section below only relevant for Cancer Council Project Officer

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