Critical appraisal:Pawlik TM, Ross MI, Prieto VG, Ballo MT, Johnson MM, Mansfield PF, et al 2006 3
Critical Appraisal
Pawlik TM, Ross MI, Prieto VG, Ballo MT, Johnson MM, Mansfield PF, et al. Assessment of the role of sentinel lymph node biopsy for primary cutaneous desmoplastic melanoma. Cancer 2006 Feb 15;106(4):900-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16411225.
Key Facts
cohort study
1. To define the incidence of DM and evaluate the results of SLNB in patients with DM
2. To analyse the effect of DM histologic subtype (pure vs. mixed) on the incidence of positive SLNs at the time of selective lymphadenectomy
1850
Non DM: n=1785
Mixed DM: n=19
SLN positive status
- Non DM: 17.5%
- Mixed DM: 19%
- Pure DM: 2.2
p<0.01 (p value refers to comparison between pure DM melanoma versus other melanomas (i.e., non-DM and mixed DM))
p=0.43 (p values refers to comparison between non-DM and mixed DM)
no
Evidence ratings
III-2
High risk of bias | Comments: Please replace this text and include any additional comments in regards to your risk of bias rating |
- Article
- Pawlik TM, Ross MI, Prieto VG, Ballo MT, Johnson MM, Mansfield PF, et al. Assessment of the role of sentinel lymph node biopsy for primary cutaneous desmoplastic melanoma. Cancer 2006 Feb 15;106(4):900-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16411225.
- Assigned to
- User:Meghna.kakani
- Topic area
- Guidelines:Melanoma
- Clinical question
Section below only relevant for Cancer Council Project Officer