Critical appraisal:Perez CA, Bauer M, Edelstein S, Gillespie BW, Birch R 1986

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Critical Appraisal

Article being appraised

Perez CA, Bauer M, Edelstein S, Gillespie BW, Birch R. Impact of tumor control on survival in carcinoma of the lung treated with irradiation. Int J Radiat Oncol Biol Phys 1986 Apr;12(4):539-47 Available from: http://www.ncbi.nlm.nih.gov/pubmed/3009368.


Applicable clinical question

Key Facts

Study Design

randomised controlled trial

Number of Patients:

0


Includes an economic evaluation

no

Evidence ratings

Level of evidence

II

Risk of bias
Moderate risk of bias Comments: Old randomised trial using outmoded techniques. Confined to stage III patients, but dose effect is relevant to all stages.


Size of effect
1 Reason for decision: Higher doses associated with significantly lower local recurrence rates.
Relevance of evidence
2 Additional comments: Effect is on local recurrence.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Professor David Ball MB BS, MD, FRANCZR


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Article
Perez CA, Bauer M, Edelstein S, Gillespie BW, Birch R. Impact of tumor control on survival in carcinoma of the lung treated with irradiation. Int J Radiat Oncol Biol Phys 1986 Apr;12(4):539-47 Available from: http://www.ncbi.nlm.nih.gov/pubmed/3009368.
Assigned to
User:David.ball
Topic area
Guidelines:Lung cancer/Treatment/Non-small-cell stage I inoperable
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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