Critical appraisal:Pohl J, Nguyen-Tat M, Manner H, Pech O, van Weyenberg SJ, Ell C 2008 2

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Critical Appraisal

Article being appraised

Pohl J, Nguyen-Tat M, Manner H, Pech O, van Weyenberg SJ, Ell C. "Dry biopsies" with spraying of dilute epinephrine optimize biopsy mapping of long segment Barrett's esophagus. Endoscopy 2008 Nov;40(11):883-7 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/18833509.


Applicable clinical question

Key Facts

Study Design

randomised controlled trial

Number of Patients:

40



Evidence ratings

Level of evidence

II

Risk of bias
Low risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: randomised controlled trial

Was the trial double-blinded?
I am reasonably certain that the trial was double-blinded (eg identical placebo, active placebo, double-dummy, no revealing side-effects).
Was the treatment allocation schedule concealed?
Adequately concealed (e.g. central randomisation, numbered or coded bottles, drugs prepared by pharmacy).
Were all randomised participants included in the analysis?
No exclusions or survival analysis used with all subjects included (>95% follow-up for all groups).
The field below is not considered when calculating the risk of bias rating
How was the allocation schedule generated?
Adequate (e.g. random number table, computer random generator, coin tossing, card shuffling)
Size of effect
2 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Eric Y Lee BSc(Med) MBBS Hons FRACP


Jutta's tick icon.png This appraisal has been completed.


Article
Pohl J, Nguyen-Tat M, Manner H, Pech O, van Weyenberg SJ, Ell C. "Dry biopsies" with spraying of dilute epinephrine optimize biopsy mapping of long segment Barrett's esophagus. Endoscopy 2008 Nov;40(11):883-7 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/18833509.
Assigned to
User:Eric.lee
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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