Critical appraisal:Prasad GA, Wang KK, Buttar NS, Wongkeesong LM, Krishnadath KK, Nichols FC 3rd, et al 2007

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Critical Appraisal

Article being appraised

Prasad GA, Wang KK, Buttar NS, Wongkeesong LM, Krishnadath KK, Nichols FC 3rd, et al. Long-term survival following endoscopic and surgical treatment of high-grade dysplasia in Barrett's esophagus. Gastroenterology 2007 Apr;132(4):1226-33 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/17408660.


Applicable clinical question

Key Facts

Study Design

case-control study

Number of Patients:

199


Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-2

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: case-control study

Subject selection
Cases
Highly selected or not described (e.g. single-institution study)
Adequacy of case definition
Taken from medical records, self report without independent validation
Controls
Selected group (e.g. hospital controls)
Comparability of groups on demographic characteristics and important potential confounders
Not comparable but adjusted analysis used
Ascertainment of exposure/treatment
No or not described
Follow-up complete and all patients included in the analysis?
Complete response
Size of effect
4 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
1 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included



Comments

Outcomes of patients with HGD treated with PDT comparable to that of oesophagectomy

Completed by

Professor Shan Rajendra MBBCh, MSc, MRCP. MD, FRCP, FRCPE, FRACP


Jutta's tick icon.png This appraisal has been completed.


Article
Prasad GA, Wang KK, Buttar NS, Wongkeesong LM, Krishnadath KK, Nichols FC 3rd, et al. Long-term survival following endoscopic and surgical treatment of high-grade dysplasia in Barrett's esophagus. Gastroenterology 2007 Apr;132(4):1226-33 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/17408660.
Assigned to
User:Darren.pavey
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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