Critical appraisal:Rana PS, Johnston DA 2000

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Critical Appraisal

Article being appraised

Rana PS, Johnston DA. Incidence of adenocarcinoma and mortality in patients with Barrett's oesophagus diagnosed between 1976 and 1986: implications for endoscopic surveillance. Dis Esophagus 2000;13(1):28-31 Available from: http://www.ncbi.nlm.nih.gov/pubmed/11005328.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

44



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Highly selected (selection at clinician's discretion regardless of whether sample consecutive), unclear or not described
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Reasonable follow-up (>80%)
Result of appraisal

Jutta's tick icon.png Included



Comments

Of 44 patients with BO, followed up for a mean period of 9.5 years (range 7-264 months), only 2 patients developed oesophageal adenocarcinoma, resulting in an incidence of one case in 209 patient-years.

Completed by

Ms Qingwei Luo


Jutta's tick icon.png This appraisal has been completed.


Article
Rana PS, Johnston DA. Incidence of adenocarcinoma and mortality in patients with Barrett's oesophagus diagnosed between 1976 and 1986: implications for endoscopic surveillance. Dis Esophagus 2000;13(1):28-31 Available from: http://www.ncbi.nlm.nih.gov/pubmed/11005328.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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