Critical appraisal:Rosmolen WD, Boer KR, de Leeuw RJ, Gamel CJ, van Berge Henegouwen MI, Bergman JJ, et al 2010

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Critical Appraisal

Article being appraised

Rosmolen WD, Boer KR, de Leeuw RJ, Gamel CJ, van Berge Henegouwen MI, Bergman JJ, et al. Quality of life and fear of cancer recurrence after endoscopic and surgical treatment for early neoplasia in Barrett's esophagus. Endoscopy 2010 Jul;42(7):525-31 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/20539974.


Applicable clinical question

Key Facts

Study Design

cohort study

Number of Patients:

91


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: This is an abstract only. The study assesses the impact on quality of life comparing resection with endoscopic therapy.

Risk of bias assessment: cohort study

Subject selection
"New technology" group
No response
Comparison group
No response
Comparability of groups on demographic characteristics and clinical features
No response
Measurement of outcomes
Outcome measures blind to technology used
No response
Same method of measurement used across comparison groups
No response
Completeness of follow-up
Was follow-up complete and were all patients included in the analysis?
No response
Size of effect
3 Reason for decision: Small numbers

The main outcome of note was that the endoscopic group had a higher "fear of cancer recurrence" than the resected group.
The resected group had more eating problems as one would expect.

Relevance of evidence
5 Additional comments: Only an abstract and not possible to do a more intensive assessment.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Associate Professor Bernard Mark Smithers


Jutta's tick icon.png This appraisal has been completed.


Article
Rosmolen WD, Boer KR, de Leeuw RJ, Gamel CJ, van Berge Henegouwen MI, Bergman JJ, et al. Quality of life and fear of cancer recurrence after endoscopic and surgical treatment for early neoplasia in Barrett's esophagus. Endoscopy 2010 Jul;42(7):525-31 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/20539974.
Assigned to
User:Bernard.smithers
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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