Critical appraisal:Rothwell PM, Wilson M, Elwin CE, Norrving B, Algra A, Warlow CP, et al 2010

This appraisal is pending.

Article

Rothwell PM, Wilson M, Elwin CE, Norrving B, Algra A, Warlow CP, et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet 2010 Nov 20;376(9754):1741-50 Available from: http://www.ncbi.nlm.nih.gov/pubmed/20970847.

Assigned to

User:Priyashiel.parikh

Topic area

Guidelines:Colorectal cancer/Primary Prevention

Clinical question

• PPR1: What is the risk-benefit ratio for use of aspirin for prevention of colorectal cancer stratified by risk of colorectal cancer itself? (What is the optimal dose and frequency of administration?)

Form

Form:Quality appraisal rct-cochrane

Outcomes

CRC mortality

Clinical trial

SALT_Trial

Notes

Critically appraise the long term follow up for the SALT-Tiral. Original trial data publication http://wiki.cancer.org.au/australia/Citation:Norrving_B,_Elwin_CE,_Peterson_B,_Blomstrand_C,_Olsson_JE,_Nilsson_B,_et_al1991

Section below only relevant for Cancer Council Project Officer

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