Critical appraisal:Rugge M, Zaninotto G, Parente P, Zanatta L, Cavallin F, Germanà B, et al 2012 2

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Critical Appraisal

Article being appraised

Rugge M, Zaninotto G, Parente P, Zanatta L, Cavallin F, Germanà B, et al. Barrett's esophagus and adenocarcinoma risk: the experience of the North-Eastern Italian Registry (EBRA). Ann Surg 2012 Nov;256(5):788-94; discussion 794-5. doi: 10.1097/SLA.0b013e3182737a7e. Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23095623.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

841



Evidence ratings

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Selected group (multiple institutions)
Subject (sample) selection
Selected group (debateable whether group is representative e.g. consecutive sample but extensive exclusion criteria)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

The study group consisted of 841 patients, 22 patients progressed to high-grade intraepithelial neoplasia or esophageal adnocarcinoma after a median of 40.2 (26.9-50.4) months.

Completed by

Ms Qingwei Luo


Jutta's tick icon.png This appraisal has been completed.


Article
Rugge M, Zaninotto G, Parente P, Zanatta L, Cavallin F, Germanà B, et al. Barrett's esophagus and adenocarcinoma risk: the experience of the North-Eastern Italian Registry (EBRA). Ann Surg 2012 Nov;256(5):788-94; discussion 794-5. doi: 10.1097/SLA.0b013e3182737a7e. Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23095623.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's/Natural history
Clinical question
Form
Form:Critical appraisal


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