Critical appraisal:Strom T, Caudell JJ, Han D, Zager JS, Yu D, Cruse CW, et al 2014 2

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Risk of bias assessment: cohort study

Subject selection
"New technology" group
Highly selected or not described
Comparison group
Highly selected or not described
Comparability of groups on demographic characteristics and clinical features
Not comparable but adjusted analysis used
Measurement of outcomes
Outcome measures blind to technology used
No, but objective measures used
Same method of measurement used across comparison groups
Completeness of follow-up
Was follow-up complete and were all patients included in the analysis?
Yes (follow-up >95%) or survival analysis using all patients
Overall risk of bias
High risk of bias Additional comments: new technology - no description on treatment selection

comparison - retrospective from one institution baseline not comparable but analysis for sub-groups made objective measures used all patients accounted for intervention analysis

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Strom T, Caudell JJ, Han D, Zager JS, Yu D, Cruse CW, et al. Radiotherapy influences local control in patients with desmoplastic melanoma. Cancer 2014 May 1;120(9):1369-78 Available from:
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Topic area
Clinical question
Form:Quality appraisal cohort

Section below only relevant for Cancer Council Project Officer

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