Critical appraisal:Strom T, Caudell JJ, Han D, Zager JS, Yu D, Cruse CW, et al 2014 3
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Critical Appraisal
Article being appraised
Strom T, Caudell JJ, Han D, Zager JS, Yu D, Cruse CW, et al. Radiotherapy influences local control in patients with desmoplastic melanoma. Cancer 2014 May 1;120(9):1369-78 Available from: http://www.ncbi.nlm.nih.gov/pubmed/24142775.
Applicable clinical question
Key Facts
Study Design
cohort study
Study aims:
To review our experience with radiotherapy in patients with desmoplastic melanoma to analyse the impact of adjuvant postoperative radiotherapy on local recurrence rates.
Number of Patients:
332
332 patients with DM.
194 patients underwent sentinel lymph node biopsy.
194 patients underwent sentinel lymph node biopsy.
Reported outcome(s):
rate of sentinel lymph node biopsy
Results of outcome(s):
28/194 patients were positive for mets (14%).
Includes an economic evaluation
no
Evidence ratings
Level of evidence
III-2
Risk of bias
High risk of bias | Comments: Please replace this text and include any additional comments in regards to your risk of bias rating |
Size of effect
5 | Reason for decision: Please replace this text and briefly describe the reasons for your rating |
Relevance of evidence
2 | Additional comments: Please replace this text and briefly describe the reasons for your rating |
Result of appraisal
Completed by
- Article
- Strom T, Caudell JJ, Han D, Zager JS, Yu D, Cruse CW, et al. Radiotherapy influences local control in patients with desmoplastic melanoma. Cancer 2014 May 1;120(9):1369-78 Available from: http://www.ncbi.nlm.nih.gov/pubmed/24142775.
- Assigned to
- User:Cecilia.taing
- Topic area
- Guidelines:Melanoma
- Clinical question
Section below only relevant for Cancer Council Project Officer