Critical appraisal:Tian J, Prasad GA, Lutzke LS, Lewis JT, Wang KK 2011

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Critical Appraisal

Article being appraised

Tian J, Prasad GA, Lutzke LS, Lewis JT, Wang KK. Outcomes of T1b esophageal adenocarcinoma patients. Gastrointest Endosc 2011 Dec;74(6):1201-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/22000793.


Applicable clinical question

Key Facts

Study Design

cohort study

Number of Patients:

68


Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-2

Risk of bias
High risk of bias Comments: Single centre retrospective review with short follow up and low patient numbers

Risk of bias assessment: cohort study

Subject selection
"New technology" group
Highly selected or not described
Comparison group
Selected group
Comparability of groups on demographic characteristics and clinical features
Comparable
Measurement of outcomes
Outcome measures blind to technology used
No, but objective measures used
Same method of measurement used across comparison groups
Yes
Completeness of follow-up
Was follow-up complete and were all patients included in the analysis?
Yes (follow-up >95%) or survival analysis using all patients
Size of effect
2 Reason for decision: Endoscopic and surgical groups not statistically different in terms of median survival duration.
Relevance of evidence
2 Additional comments: Compares endoscopic therapy and surgery outcomes specific for T1b EOA.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Farzan Fahrtash Bahin, MBBS (Hons), MPhil (Med)


Jutta's tick icon.png This appraisal has been completed.


Article
Tian J, Prasad GA, Lutzke LS, Lewis JT, Wang KK. Outcomes of T1b esophageal adenocarcinoma patients. Gastrointest Endosc 2011 Dec;74(6):1201-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/22000793.
Assigned to
User:Michael.bourke
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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