Critical appraisal:Van Hezewijk M, Creutzberg CL, Putter H, Chin A, Schneider I, Hoogeveen M, et al 2010 6

Risk of bias assessment: cohort study

Subject selection

"New technology" group

Highly selected or not described

Comparison group

Highly selected or not described

Comparability of groups on demographic characteristics and clinical features

Comparable

Measurement of outcomes

Outcome measures blind to technology used

No or not described

Same method of measurement used across comparison groups

Yes

Completeness of follow-up

Was follow-up complete and were all patients included in the analysis?

Yes (follow-up >95%) or survival analysis using all patients

Overall risk of bias

High risk of bias

Additional comments:

This appraisal has been completed.

Article

van Hezewijk M, Creutzberg CL, Putter H, Chin A, Schneider I, Hoogeveen M, et al. Efficacy of a hypofractionated schedule in electron beam radiotherapy for epithelial skin cancer: Analysis of 434 cases. Radiother Oncol 2010 May;95(2):245-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/20334941.

Assigned to

User:Annika.stollery

Topic area

Guidelines:Keratinocyte carcinoma

Clinical question

• In which patients with cutaneous squamous cell carcinoma does a radiotherapy modality achieve equal or better outcomes than conventional surgery?

Form

Form:Quality appraisal cohort

Outcomes

- Cosmetic effects; - Local recurrence-free rate; - Metastases free rate; - Overall survival; - Cancer specific survival

Section below only relevant for Cancer Council Project Officer

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