Critical appraisal:Van der Veen AH, Dees J, Blankensteijn JD, Van Blankenstein M 1989

From Cancer Guidelines Wiki

Critical Appraisal

Article being appraised

Van der Veen AH, Dees J, Blankensteijn JD, Van Blankenstein M. Adenocarcinoma in Barrett's oesophagus: an overrated risk. Gut 1989 Jan;30(1):14-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/2920919.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

166



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

In this retrospective study of all patients with Barrett's oesophagus diagnosed in a 12 year period carcinoma had developed in only four patients. The incidence of oesophageal cancer in this series was one in 170 patient years, which means a 30-fold increase compared with the general population. The survival of patients with Barrett's oesophagus was not different, however, from an age and sex matched control population. It is concluded that systematic endoscopic surveillance of patients with Barrett's oesophagus is not indicated.There are, however, indications that there are subgroups of patients which are specially at risk.

Completed by

Erfan Jaberiyanfar


Jutta's tick icon.png This appraisal has been completed.


Article
Van der Veen AH, Dees J, Blankensteijn JD, Van Blankenstein M. Adenocarcinoma in Barrett's oesophagus: an overrated risk. Gut 1989 Jan;30(1):14-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/2920919.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment