Critical appraisal:Van der Veen AH, Dees J, Blankensteijn JD, Van Blankenstein M 1989
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Critical Appraisal
Article being appraised
Van der Veen AH, Dees J, Blankensteijn JD, Van Blankenstein M. Adenocarcinoma in Barrett's oesophagus: an overrated risk. Gut 1989 Jan;30(1):14-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/2920919.
Applicable clinical question
Key Facts
Study Design
prevalence and incidence study
Number of Patients:
166
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| High risk of bias | Comments: Please replace this text and include any additional comments in regards to your quality rating |
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- Article
- Van der Veen AH, Dees J, Blankensteijn JD, Van Blankenstein M. Adenocarcinoma in Barrett's oesophagus: an overrated risk. Gut 1989 Jan;30(1):14-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/2920919.
- Assigned to
- User:Freddy.sitas
- Topic area
- Guidelines:Barrett's
- Clinical question
Section below only relevant for Cancer Council Project Officer
In this retrospective study of all patients with Barrett's oesophagus diagnosed in a 12 year period carcinoma had developed in only four patients. The incidence of oesophageal cancer in this series was one in 170 patient years, which means a 30-fold increase compared with the general population. The survival of patients with Barrett's oesophagus was not different, however, from an age and sex matched control population. It is concluded that systematic endoscopic surveillance of patients with Barrett's oesophagus is not indicated.There are, however, indications that there are subgroups of patients which are specially at risk.