Critical appraisal:Vieth M, Schubert B, Lang-Schwarz K, Stolte M 2006
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Critical Appraisal
Article being appraised
Vieth M, Schubert B, Lang-Schwarz K, Stolte M. Frequency of Barrett's neoplasia after initial negative endoscopy with biopsy: a long-term histopathological follow-up study. Endoscopy 2006 Dec;38(12):1201-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17163319.
Applicable clinical question
Key Facts
Study Design
prevalence and incidence study
Number of Patients:
1071
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| High risk of bias | Comments: Please replace this text and include any additional comments in regards to your quality rating |
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- Article
- Vieth M, Schubert B, Lang-Schwarz K, Stolte M. Frequency of Barrett's neoplasia after initial negative endoscopy with biopsy: a long-term histopathological follow-up study. Endoscopy 2006 Dec;38(12):1201-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17163319.
- Assigned to
- User:Freddy.sitas
- Topic area
- Guidelines:Barrett's
- Clinical question
Section below only relevant for Cancer Council Project Officer
In the study cases (male:female ratio 2.1:1, mean age ?SD 60.9 ? 14.2 years), the biopsy procedure was fully compliant with guidelines in only 32.5%. Only 5 cases (0.6 %) had visible lesions reported on endoscopy, but all were negative for neoplasia.Differences between SSBE and LSBE were only encountered for cancer incidence. The yearly incidence of Barrett esophagus cancer varies between 0.4% and 1.7 %.