Critical appraisal:Vieth M, Schubert B, Lang-Schwarz K, Stolte M 2006

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Critical Appraisal

Article being appraised

Vieth M, Schubert B, Lang-Schwarz K, Stolte M. Frequency of Barrett's neoplasia after initial negative endoscopy with biopsy: a long-term histopathological follow-up study. Endoscopy 2006 Dec;38(12):1201-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17163319.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

1071



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

In the study cases (male:female ratio 2.1:1, mean age ?SD 60.9 ? 14.2 years), the biopsy procedure was fully compliant with guidelines in only 32.5%. Only 5 cases (0.6 %) had visible lesions reported on endoscopy, but all were negative for neoplasia.Differences between SSBE and LSBE were only encountered for cancer incidence. The yearly incidence of Barrett esophagus cancer varies between 0.4% and 1.7 %.

Completed by

Erfan Jaberiyanfar


Jutta's tick icon.png This appraisal has been completed.


Article
Vieth M, Schubert B, Lang-Schwarz K, Stolte M. Frequency of Barrett's neoplasia after initial negative endoscopy with biopsy: a long-term histopathological follow-up study. Endoscopy 2006 Dec;38(12):1201-5 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17163319.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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