Critical appraisal:Von Rahden BH, Stein HJ, Weber A, Vieth M, Stolte M, Rösch T, et al 2008 3

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Critical Appraisal

Article being appraised

von Rahden BH, Stein HJ, Weber A, Vieth M, Stolte M, Rösch T, et al. Critical reappraisal of current surveillance strategies for Barrett's esophagus: analysis of a large German Barrett's database. Dis Esophagus 2008;21(8):685-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18847456.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

1438



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Selected group (multiple institutions)
Subject (sample) selection
Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
No or not described
Result of appraisal

Jutta's tick icon.png Included



Comments

Either HG-IN or Ca (‘malignant BE’) was detected in altogether 28 cases (1.9%) during a median follow-up of 24 months (range 1–255), accounting for an incidence
of 0.95% per year of follow-up. Analysis per group revealed a significantly higher incidence (P < 0.001, c2-test) of HG-IN/Ca in the LG-IN group (n = 11, 19.3%) compared with the group of patients with non-neoplastic BE (n = 17, 1.2%; see Table 2).

Completed by

Erfan Jaberiyanfar


Jutta's tick icon.png This appraisal has been completed.


Article
von Rahden BH, Stein HJ, Weber A, Vieth M, Stolte M, Rösch T, et al. Critical reappraisal of current surveillance strategies for Barrett's esophagus: analysis of a large German Barrett's database. Dis Esophagus 2008;21(8):685-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18847456.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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