Critical appraisal:Wang VS, Hornick JL, Sepulveda JA, Mauer R, Poneros JM 2009

Critical Appraisal

Article being appraised

Wang VS, Hornick JL, Sepulveda JA, Mauer R, Poneros JM. Low prevalence of submucosal invasive carcinoma at esophagectomy for high-grade dysplasia or intramucosal adenocarcinoma in Barrett's esophagus: a 20-year experience. Gastrointest Endosc 2009 Apr;69(4):777-83 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19136106.

Applicable clinical question

• What is the incidence of neoplasia in patients with BO?

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

60

Evidence ratings

Risk of bias

High risk of bias

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Risk of bias assessment: prevalence and incidence study

Source population of patients

Highly selected (single institution) or not described

Subject (sample) selection

Selected group (debateable whether group is representative e.g. consecutive sample but extensive exclusion criteria)

Measurement of condition

Objective and reliable (based on registry or other equivalent source)

Follow-up complete and all patients included in the analysis?

Yes (follow-up >95%)

Result of appraisal

Included

Comments

1 case detected

Completed by

Associate Professor Freddy Sitas

This appraisal has been completed.

Article

Wang VS, Hornick JL, Sepulveda JA, Mauer R, Poneros JM. Low prevalence of submucosal invasive carcinoma at esophagectomy for high-grade dysplasia or intramucosal adenocarcinoma in Barrett's esophagus: a 20-year experience. Gastrointest Endosc 2009 Apr;69(4):777-83 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19136106.

Assigned to

User:Freddy.sitas

Topic area

Guidelines:Barrett's

Clinical question

• What is the incidence of neoplasia in patients with BO?

Form

Form:Critical appraisal

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