Critical appraisal:Wani S, Falk GW, Post J, Yerian L, Hall M, Wang A, et al 2011
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Critical Appraisal
Article being appraised
Wani S, Falk GW, Post J, Yerian L, Hall M, Wang A, et al. Risk factors for progression of low-grade dysplasia in patients with Barrett's esophagus. Gastroenterology 2011 Oct;141(4):1179-86, 1186.e1 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21723218.
Applicable clinical question
Key Facts
Study Design
prevalence and incidence study
Number of Patients:
210
Evidence ratings
Risk of bias
| Moderate risk of bias | Comments: Please replace this text and include any additional comments in regards to your quality rating |
Result of appraisal
Included
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- Article
- Wani S, Falk GW, Post J, Yerian L, Hall M, Wang A, et al. Risk factors for progression of low-grade dysplasia in patients with Barrett's esophagus. Gastroenterology 2011 Oct;141(4):1179-86, 1186.e1 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21723218.
- Assigned to
- User:Freddy.sitas
- Topic area
- Guidelines:Barrett's
- Clinical question
Section below only relevant for Cancer Council Project Officer
Of the 210 patients included in the study, 6 patients developed esphageal adenocarcinoma with a incidence rate of 0.44% per year (0.2-0.98). Mean FUP of 6.22 years for a total of 959.6 patient-years.