Critical appraisal:Weston AP, Krmpotich PT, Cherian R, Dixon A, Topalosvki M 1997

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Critical Appraisal

Article being appraised

Weston AP, Krmpotich PT, Cherian R, Dixon A, Topalosvki M. Prospective long-term endoscopic and histological follow-up of short segment Barrett's esophagus: comparison with traditional long segment Barrett's esophagus. Am J Gastroenterol 1997 Mar;92(3):407-13 Available from: http://www.ncbi.nlm.nih.gov/pubmed/9068459.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

152



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Reasonable follow-up (>80%)
Result of appraisal

Jutta's tick icon.png Included



Comments

The prevalence of dysplasia at diagnosis in patients with short segment Barrett's was 8.1% versus 24.4% in patients with traditional Barrett's ( p < 0.007). Adenocarcinoma was noted at diagnosis only in patients with traditional Barrett's ( p < 0.0005). Dysplasia developed during follow-up in two patients with short segment Barrett's and in six patients with traditional Barrett's ( p < 0.05).
The prevalence of dysplasia or adenocarcinoma and the incidence of dysplasia in patients with traditional Barrett's esophagus are significantly higher than in patients with short segment Barrett's esophagus.

Completed by

Erfan Jaberiyanfar


Jutta's tick icon.png This appraisal has been completed.


Article
Weston AP, Krmpotich PT, Cherian R, Dixon A, Topalosvki M. Prospective long-term endoscopic and histological follow-up of short segment Barrett's esophagus: comparison with traditional long segment Barrett's esophagus. Am J Gastroenterol 1997 Mar;92(3):407-13 Available from: http://www.ncbi.nlm.nih.gov/pubmed/9068459.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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