Critical appraisal:Williamson WA, Ellis FH Jr, Gibb SP, Shahian DM, Aretz HT, Heatley GJ, et al 1991

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Critical Appraisal

Article being appraised

Williamson WA, Ellis FH Jr, Gibb SP, Shahian DM, Aretz HT, Heatley GJ, et al. Barrett's esophagus. Prevalence and incidence of adenocarcinoma. Arch Intern Med 1991 Nov;151(11):2212-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/1953225.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

176



Evidence ratings

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Highly selected (single institution) or not described
Subject (sample) selection
Highly selected (selection at clinician's discretion regardless of whether sample consecutive), unclear or not described
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

A total of 176 patients with BO from single Medical Centre, followed up for a total of 497 patient-years, 5 patients developed adenocarcinoma for an incidence of 1/99 patient-years.

Completed by

Ms Qingwei Luo


Jutta's tick icon.png This appraisal has been completed.


Article
Williamson WA, Ellis FH Jr, Gibb SP, Shahian DM, Aretz HT, Heatley GJ, et al. Barrett's esophagus. Prevalence and incidence of adenocarcinoma. Arch Intern Med 1991 Nov;151(11):2212-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/1953225.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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