Critical appraisal:Williamson WA, Ellis FH Jr, Gibb SP, Shahian DM, Aretz HT, Heatley GJ, et al 1991

Critical Appraisal

Article being appraised

Williamson WA, Ellis FH Jr, Gibb SP, Shahian DM, Aretz HT, Heatley GJ, et al. Barrett's esophagus. Prevalence and incidence of adenocarcinoma. Arch Intern Med 1991 Nov;151(11):2212-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/1953225.

Applicable clinical question

• What is the incidence of neoplasia in patients with BO?

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

176

Evidence ratings

Risk of bias

High risk of bias

Comments: Please replace this text and include any additional comments in regards to your quality rating

Show/Hide Risk of bias assessment

Risk of bias assessment: prevalence and incidence study

Source population of patients

Highly selected (single institution) or not described

Subject (sample) selection

Highly selected (selection at clinician's discretion regardless of whether sample consecutive), unclear or not described

Measurement of condition

Objective and reliable (based on registry or other equivalent source)

Follow-up complete and all patients included in the analysis?

Yes (follow-up >95%)

Result of appraisal

Included

Comments

A total of 176 patients with BO from single Medical Centre, followed up for a total of 497 patient-years, 5 patients developed adenocarcinoma for an incidence of 1/99 patient-years.

Completed by

Ms Qingwei Luo

This appraisal has been completed.

Article

Williamson WA, Ellis FH Jr, Gibb SP, Shahian DM, Aretz HT, Heatley GJ, et al. Barrett's esophagus. Prevalence and incidence of adenocarcinoma. Arch Intern Med 1991 Nov;151(11):2212-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/1953225.

Assigned to

User:Freddy.sitas

Topic area

Guidelines:Barrett's

Clinical question

• What is the incidence of neoplasia in patients with BO?

Form

Form:Critical appraisal

Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment