Critical appraisal:Wright G, Manser RL, Byrnes G, Hart D, Campbell DA 2006

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Critical Appraisal

Article being appraised

Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for non-small cell lung cancer: systematic review and meta-analysis of randomised controlled trials. Thorax 2006 Jul;61(7):597-603 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16449262.


Applicable clinical question

Key Facts

Study Design

systematic review — Reandomised controlled trials only

Number of Patients:

848


Includes an economic evaluation

no

Evidence ratings

Level of evidence

I

Risk of bias
Low risk of bias Comments: Cochrane Review


Size of effect
1 Reason for decision: A clinically important benefit for the full range of plausible estimates. The confidence limit closest to the measure of no effect (the ‘null’) rules out a clinically unimportant effect of the intervention.
Relevance of evidence
1 Additional comments: Evidence of an effect on patient‐relevant clinical outcomes including benefits and harms, quality of life and survival.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Associate Professor Gavin Wright MD FRACS PhD


Jutta's tick icon.png This appraisal has been completed.


Article
Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for non-small cell lung cancer: systematic review and meta-analysis of randomised controlled trials. Thorax 2006 Jul;61(7):597-603 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16449262.
Assigned to
User:Gavin.wright
Topic area
Guidelines:Lung cancer/Treatment/Non-small-cell stage I operable
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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