Critical appraisal:Wright G, Manser RL, Byrnes G, Hart D, Campbell DA 2006
From Cancer Guidelines Wiki
Critical Appraisal
Article being appraised
Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for non-small cell lung cancer: systematic review and meta-analysis of randomised controlled trials. Thorax 2006 Jul;61(7):597-603 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16449262.
Applicable clinical question
Key Facts
Study Design
systematic review — Reandomised controlled trials only
Number of Patients:
848
Includes an economic evaluation
no
Evidence ratings
Level of evidence
I
Risk of bias
Low risk of bias | Comments: Cochrane Review |
Size of effect
1 | Reason for decision: A clinically important benefit for the full range of plausible estimates. The confidence limit closest to the measure of no effect (the ‘null’) rules out a clinically unimportant effect of the intervention. |
Relevance of evidence
1 | Additional comments: Evidence of an effect on patient‐relevant clinical outcomes including benefits and harms, quality of life and survival. |
Result of appraisal
Completed by
- Article
- Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for non-small cell lung cancer: systematic review and meta-analysis of randomised controlled trials. Thorax 2006 Jul;61(7):597-603 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16449262.
- Assigned to
- User:Gavin.wright
- Topic area
- Guidelines:Lung cancer/Treatment/Non-small-cell stage I operable
- Clinical question
Section below only relevant for Cancer Council Project Officer