Critical appraisal:Wright G, Manser RL, Byrnes G, Hart D, Campbell DA 2006 3
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Critical Appraisal
Article being appraised
Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for non-small cell lung cancer: systematic review and meta-analysis of randomised controlled trials. Thorax 2006 Jul;61(7):597-603 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16449262.
Applicable clinical question
Key Facts
Study Design
systematic review — Randomised trials only
Number of Patients:
848
Includes an economic evaluation
no
Evidence ratings
Level of evidence
I
Risk of bias
| Low risk of bias | Comments: Report of cochrane review |
Size of effect
| 1 | Reason for decision: A clinically important benefit for the full range of plausible estimates. The confidence limit closest to the measure of no effect (the ‘null’) rules out a clinically unimportant effect of the intervention. |
Relevance of evidence
| 1 | Additional comments: Evidence of an effect on patient‐relevant clinical outcomes including benefits and harms, quality of life and survival. |
Result of appraisal
Included
Completed by
This appraisal has been completed.
- Article
- Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for non-small cell lung cancer: systematic review and meta-analysis of randomised controlled trials. Thorax 2006 Jul;61(7):597-603 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16449262.
- Assigned to
- User:Gavin.wright
- Topic area
- Guidelines:Lung cancer/Treatment/Non-small-cell stage III operable
- Clinical question
Section below only relevant for Cancer Council Project Officer