Critical appraisal:Wright TA, Gray MR, Morris AI, Gilmore IT, Ellis A, Smart HL, et al 1996

Critical Appraisal

Article being appraised

Wright TA, Gray MR, Morris AI, Gilmore IT, Ellis A, Smart HL, et al. Cost effectiveness of detecting Barrett's cancer. Gut 1996 Oct;39(4):574-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/8944568.

Applicable clinical question

• What is the incidence of neoplasia in patients with BO?

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

301

Evidence ratings

Risk of bias

High risk of bias

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Risk of bias assessment: prevalence and incidence study

Source population of patients

Highly selected (single institution) or not described

Subject (sample) selection

Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)

Measurement of condition

Objective and reliable (based on registry or other equivalent source)

Follow-up complete and all patients included in the analysis?

Yes (follow-up >95%)

Result of appraisal

Included

Comments

A total of 301 patients with BO were included, 55% entred the prospective surveillance programme. Six patients developed adenocarcinoma of the oesophagus - an incidence of 1/59 male and 1/167 female patient-years of FUP.

Completed by

Ms Qingwei Luo

This appraisal has been completed.

Article

Wright TA, Gray MR, Morris AI, Gilmore IT, Ellis A, Smart HL, et al. Cost effectiveness of detecting Barrett's cancer. Gut 1996 Oct;39(4):574-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/8944568.

Assigned to

User:Freddy.sitas

Topic area

Guidelines:Barrett's

Clinical question

• What is the incidence of neoplasia in patients with BO?

Form

Form:Critical appraisal

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