Critical appraisal:Wu J, Pan YM, Wang TT, Gao DJ, Hu B 2013

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Critical Appraisal

Article being appraised

Wu J, Pan YM, Wang TT, Gao DJ, Hu B. Endotherapy versus surgery for early neoplasia in Barrett's esophagus: a meta-analysis. Gastrointest Endosc 2013 Sep 27 Available from: http://www.ncbi.nlm.nih.gov/pubmed/24079410.


Applicable clinical question

Key Facts

Study Design

systematic review — non-randomised trials

Number of Patients:

870


Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-1

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: systematic review

Studies included in the review
Was an adequate search strategy used?
Adequate – search terms and/or choice of databases could have been improved upon
Were the inclusion criteria appropriate and applied in an unbiased way?
Yes – pre-specified inclusion criteria applied independently by two people
Were the studies assessed for quality (relating to the minimisation of biases)?
Yes – appropriate quality issues were assessed independently by two people
Were the characteristics and results of individual studies appropriately summarised?
Yes – summary descriptive tables of subjects, interventions, outcomes etc are provided and estimates of treatment effect displayed
The following questions are only relevant for systematic reviews that pooled data
Were the methods used for pooling the data appropriate?
Yes
If there was heterogeneity, were sources of heterogeneity explored?
Some attempt was made
Size of effect
2 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
2 Additional comments: Compares surgery to endotherapy - bot specific to EOA
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Farzan Fahrtash Bahin, MBBS (Hons), MPhil (Med)


Jutta's tick icon.png This appraisal has been completed.


Article
Wu J, Pan YM, Wang TT, Gao DJ, Hu B. Endotherapy versus surgery for early neoplasia in Barrett's esophagus: a meta-analysis. Gastrointest Endosc 2013 Sep 27 Available from: http://www.ncbi.nlm.nih.gov/pubmed/24079410.
Assigned to
User:Michael.bourke
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment