Critical appraisal:Yee S 2016 2
Yee S. Factors associated with the receipt of fertility preservation services along the decision-making pathway in young Canadian female cancer patients. J Assist Reprod Genet 2016 Feb;33(2):265-80 Available from: http://www.ncbi.nlm.nih.gov/pubmed/26560157.
- Do patients who are referred to fertility specialists experience less decisional conflict? Are they more likely to access fertility preservation treatments?
cross sectional study
Assessed whether there is an association between the uptake of FP procedure and the quality of pre-FPC fertility
discussion with oncologist.
143 of the 188 participants had a fertility discussion with the oncologist. 72 participants self-initiated the FP discussion.
Degree of fertility concern at diagnosis 1.81 (1.38 to 2.38, p<.05) was found to be significant in the final regression model. Women who found their oncologists supportive of their FP plan were nine times more likely to proceed with FP compared to those who found their oncologists either non-supportive or neutral (OR 9.61, CI 1.60 to 57.85, p<.05). The odds increased by more than five times for each additional increment on the 5-point Likert scale examining their fertility concern at the time of cancer diagnosis (OR 5.5, CI: 1.45 to 21.05, p<.05).
- Susceptible to bias due to potential misclassification due to recall bias.
- Cannot identify if the characteristics of non-responders differ from responders, which can result in bias of the measures of outcome.
|Moderate risk of bias||Comments: - Non-probability convenience sampling was used to recruit potential participants through cancer organizations and survivor networks - no response rate available.
- Very wide retrospective recruitment timeframe (from 2000). - Risk of recall bias is high for this study - one quarter (n=45, 23.9 %) did not recall having a fertility discussion with their oncologists.
|4||Reason for decision:|
High risk of bias
- Yee S. Factors associated with the receipt of fertility preservation services along the decision-making pathway in young Canadian female cancer patients. J Assist Reprod Genet 2016 Feb;33(2):265-80 Available from: http://www.ncbi.nlm.nih.gov/pubmed/26560157.
- Assigned to
- Topic area
- Guidelines:COSA:Cancer fertility preservation guidelines/Referral to fertility specialists
- Clinical question
Section below only relevant for Cancer Council Project Officer