Critical appraisal:Yeh RW, Gerson LB, Triadafilopoulos G 2003 2

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Critical Appraisal

Article being appraised

Yeh RW, Gerson LB, Triadafilopoulos G. Efficacy of esomeprazole in controlling reflux symptoms, intraesophageal, and intragastric pH in patients with Barrett's esophagus. Dis Esophagus 2003;16(3):193-8 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/14641308.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

13


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
No or not described
Follow-up complete and all patients included in the analysis?
No or not described
Size of effect
1 Reason for decision: Symptoms significantly reduced on PPI compared to off PPI
Relevance of evidence
1 Additional comments: Patients completed reflux questionnaire and QOL assessment
Result of appraisal

Jutta's tick icon.png Included




Completed by

Associate Professor Geoffrey Hebbard


Jutta's tick icon.png This appraisal has been completed.


Article
Yeh RW, Gerson LB, Triadafilopoulos G. Efficacy of esomeprazole in controlling reflux symptoms, intraesophageal, and intragastric pH in patients with Barrett's esophagus. Dis Esophagus 2003;16(3):193-8 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/14641308.
Assigned to
User:Geoffrey.hebbard
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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