Surveillance colonoscopy

Glossary and abbreviations

From Cancer Guidelines Wiki

Abbreviations[edit source]

Abbreviation Term
AN Advanced neoplasia (advanced adenoma or colorectal cancer)
ASP Advanced serrated polyp
AGA American Gastroenterological Association
ACPGBI Association of Coloproctology of Great Britain and Ireland
BMI Body mass index
BPPS Boston bowel preparation scale
BSG British Society of Gastroenterology
CRC Colorectal cancer
CCRTGE Conjoint Committee for the Recognition of Training in Gastrointestinal Endoscopy
CA Conventional adenoma
DNA Deoxyribonucleic acid
DALM Dysplasia associated lesion mass
EMR Endoscopic mucosal resection
ESD Endoscopic submucosal dissection
EPoS European Polyp Surveillance trials
ESGE European Society for Gastroenterology
FICE Fujinon intelligent chromoendoscopy
GESA Gastroenterological Society of Australia
HGD High grade dysplasia
HRA High risk adenoma
HDL High-density lipoprotein
HPP/HP Hyperplastic polyp
ID Indefinite dysplasia
IBD Inflammatory bowel disease
KRAS Kirsten rat sarcoma
LSL Laterally spreading lesion/s
LGD Low grade dysplasia
LRA Low risk adenoma
MP Malignant polyp
MA Metachronous adenoma
MAA Metachronous advanced adenoma
MAN Metachronous advanced neoplasia
MN Metachronous neoplasia
MMR Mismatch repair 
NHMRC National Health and Medical Research Council
NPS National Polyp Study
NAA Non-advanced adenoma
OC Optical colonoscopy
PEG Polyethylene glycol 
PICO Population, intervention, comparison, outcome
PCP Primary care physicians
PSC Primary sclerosing cholangitis
RR Relative risk
RANZCR Royal Australian and New Zealand College of Radiologists
SP Serrated polyp
SES Socioeconomic status
SIR Standardised incidence ratio
SMR Standardised mortality ratio
STAI-S State Trait Anxiety Inventory
SMI Submucosal invasion
SCENIC Surveillance for colorectal endoscopic neoplasia detection and management in inflammatory bowel disease patients: International Consensus recommendations
SEER Surveillance, Epidemiology and End Results
TSA Traditional serrated adenoma
TP53 Tumour suppressor p53
UC Ulcerative colitis
UK United Kingdom
USMTF US Multi-Society Task Force
USA United States of America
WLE White light endoscopy
WASP Workgroup serrAted polypS and Polyposis
WHO World Health Organization

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Glossary terms[edit source]

Term Definition
Abdominoperineal resection An operation for rectal cancer. This involves removing part of the colon, rectum and anus, and creating a permanent colostomy.
Absolute risk The risk a subject has for developing the tested disease over a stated time period.
Adenocarcinoma A type of cancerous tumour that forms from glandular structures in epithelial tissue.
Adenoma detection rate (ADR) The proportion of individuals undergoing a complete screening colonoscopy who have one or more adenomas, or polyps, detected. Variously defined according to context but most often defined as the proportion of patients aged 50 and over having screening colonoscopy found to have at least one adenomatous polyp.
Adenomatous Polyposis Coli (APC) A multifunctional tumour suppressor gene. Mutations in this gene are responsible for familial adenomatous polyposis and contributes to many sporadic colorectal cancers. 
Adjuvant therapy A treatment given with or shortly after another treatment to make it more effective. This usually refers to surgery followed by chemotherapy or radiotherapy.
Advanced adenoma (AA) An adenoma that measures 10mm or more in size. Includes adenomatous polyps greater than or equal to 10 mm in size or with a significant villous component or with high-grade dysplasia.
Anterior resection A surgical procedure to remove cancer in the rectum with the bowel being re-joined to leave a functioning anus.
Biopsy The removal of a small sample of tissue from the body for examination under a microscope to help diagnose a disease.
Bowel cancer Cancer of the large bowel; also known as colorectal cancer, colon cancer or rectal cancer.
Bowel preparation The process of cleaning out the bowel before a test, scan or operation to allow the doctor to see the bowel more clearly.
Carcinoembryonic antigen (CEA) A protein that may be found in the blood of a person with colorectal cancer.
Chemoprophylaxis Administration of a medication or drug to prevent disease.
Colectomy The surgical removal of all or part of the colon. The affected areas of the colon are cut out and the two ends are joined back together. Colectomies are named for the part removed. They include: right and left hemicolectomies and transverse, sigmoid, subtotal and total colectomies.
Colon The main part of the large bowel, which absorbs water and electrolytes from undigested food (solid waste). Its four parts are the ascending colon, transverse colon, descending colon and sigmoid colon.
Colonoscopy An examination of the large bowel using a camera on a flexible tube, which is passed through the anus.
Colorectal Referring to the large bowel, comprising the colon and rectum.
Confidence interval (CI) A measure that quantifies the uncertainty in measurement. When reported as 95% CI, it is the range of values within which we can be 95% sure that the true value for the whole population lies.
Confocal laser endomicroscopy (CLE) An endoscopy procedure that uses a specialised endoscope capable of visualising the mucosal layer of the colon at very high magnification.
Consensus-based recommendation A recommendation formulated in the absence of quality evidence, after a systematic review of the evidence was conducted and failed to identify admissible evidence on the clinical question.
CT colonography Also known as virtual colonoscopy, a medical imaging procedure that uses low dose radiation computerised tomography (CT) scanning to obtain an interior view of the colon (the large bowel) that is otherwise only seen with a more invasive procedure such as colonoscopy where an endoscope is inserted into the rectum and passed through the entire colon.
CT scan A computerised tomography (CT) scan, in which x-ray equipment is used to create detailed digital images, or scans, of areas inside the body.
Distant metastasis Cancer that has spread from the original (primary) tumour to distant organs or distant lymph nodes.
Electronic chromoendoscopy (EC)  An endoscopic procedure using a specialised endoscope that provides a detailed contrast enhancement image of the musical surface of the colon, and includes NBI, FICE or i-SCAN.
Evidence-based recommendation A recommendation formulated after a systematic review of the evidence, indicating supporting references.
Faecal occult blood test A test that can detect microscopic amounts of blood in stools. The most common type of FOBT is the immunochemical FOBT (iFOBT), which directly detect haemoglobin using antibodies specific for the globin moiety of human haemoglobin.
Familial adenomatous polyposis (FAP) An autosomal dominant inherited condition in which numerous polyps form mainly in the colon.
Familial syndromes Genetic disorders in which inherited genetic mutations in one or more genes predispose a person to developing cancer, particularly at an early age.
First degree relative (FDR) An individual’s full siblings, parents or children.
Flexible sigmoidoscopy A procedure to examine the inner lining of the rectum and lower portion of the colon using a flexible tube, usually a colonoscope (unlike the colonoscopy that examines the entirety of the colon). The tube is approximately 60 cm long, has a small light and a camera attached at the tip of the tube.
Full spectrum endoscopy (FUSE)  An endoscope with a viewing angle of 330°.
Functional gastrointestinal disease (FGID)  Also known as functional gastrointestinal disorders. A group of bowel disorders which are characterised by persistent and recurring gastrointestinal symptoms in the absence of demonstrable organic pathology.
General practitioner (GP) A medical professional who treats acute and chronic illnesses and provides preventive care and health education to a wide range of patients.
Hazard ratio (HR) A measure of how often a particular event happens in one group compared to how often it happens in another group, over time. In cancer research, hazard ratios are often used in clinical trials to measure survival at any particular moment in a group of patients who have been given a specific treatment or a placebo.
Imaging Using scans, including nuclear medicine, to create images of the interior of a body for clinical analysis and medical intervention.
Incidence An epidemiological term reporting number of new cases in a population within a specified period.
Interval cancer (IC) A cancer whose presence is diagnosed in the time between scheduled screening tests or surveillance procedures.
Laparoscopic approach A procedure where small multiple incisions are made to perform an operation, rather than making a large open incision.
Local recurrence The reappearance of cancer at a site that was previously treated and responded to therapy.
MAPK pathway A chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus.
Metabolic syndrome Metabolic syndrome is a collection of conditions that often occur together and increase the risk of diabetes, stroke and heart disease. The main components of metabolic syndrome include obesity, high blood pressure, high blood triglycerides, low levels of HDL cholesterol and insulin resistance.
Metastatic Cancer that has spread from the primary site of origin (where it started) into different area(s) of the body.
mut-L homolog 1 (MLH1) A gene commonly associated with Lynch syndrome and functions in repairing DNA mismatches.
Narrow band imaging (NBI) A specialised type of endoscopy that uses specific blue and green wavelengths of light to enhance visualisation of the mucosal layer of the colon.
National Bowel Cancer Screening Program (NBCSP) An Australian screening program that aims to reduce illness and death from bowel cancer through early detection or prevention of the disease.
Negative predictive value (NPV) The probability that a subject with a negative screening test result truly does not have the condition for which they are being tested.
Odds ratio (OR) A comparison of the odds (probability) of something happening in one group with the odds of it happening in another.
Pathology A medical specialty that determines the cause and nature of diseases by examining and testing body tissues, for instance from laboratory examination of samples of body tissue.
Peri-operative Measures or interventions used at or around the time of an operation to improve patient outcomes.
Polyp A small growth protruding from a mucous membrane, such as the lining of the bowel.
Polypectomy The removal of polyps from the bowel.
Positive predictive value (PPV) A measure for the probability that a subject with a positive screening result truly has the disease for which they are being tested.
Practice point A recommendation on a subject that is outside the scope of the search strategy for the systematic review, based on expert opinion and formulated by a consensus process.
Proctocolectomy A surgical procedure to remove the colon and rectum.
Randomised controlled trial (RCT) A study in which people are allocated at random (by chance alone) to receive one of several clinical interventions. One of these interventions is the standard of comparison or control.
Rectal endoscopic ultrasound An imaging procedure where a probe is inserted into the rectum and high frequency sound waves (ultrasound waves) are generated to look for abnormalities in the rectum and nearby structures.
Rectum The final section of the large bowel, ending at the anus.
Second degree relative (SDR) Someone who shares 25% of a person’s genes, such as uncles, aunts, grandparents, half-siblings
Villosity The state of being villous, a histopathological feature of some tubular adenomas. Villous adenoma is a type of polyp found in the colon or rectum that appear as a cauliflower-like mass.

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